Suppressing the DSCAM/PAK1 pathway reverses neurogenesis deficits in Down Syndrome patient iPSC-derived cerebral organoids.
Tang X-Y, Xu L, Wang J, Hong Y, Wang Y, Zhu Q, Wang D, Zhang X-Y, Liu C-Y, Fang K-H, et al. Suppressing the DSCAM/PAK1 pathway reverses neurogenesis deficits in Down Syndrome patient iPSC-derived cerebral organoids. J Clin Invest. 2021.