Biblio

Author Title Type [ Year(Asc)]
Filters: Author is Melton, Douglas A  [Clear All Filters]
2022
Leite NC, Pelayo GC, Melton DA. Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro. Stem Cell Reports. 2022.
Sintov E, Nikolskiy I, Barrera V, Kenty JHyoje-Ryu, Atkin AS, Gerace D, Sui SJHo, Boulanger K, Melton DA. Whole-genome CRISPR screening identifies genetic manipulations to reduce immune rejection of stem cell-derived islets. Stem Cell Reports. 2022.
2021
Sintov E, Gerace D, Melton DA. A human ESC line for efficient CRISPR editing of pluripotent stem cells. Stem Cell Res. 2021;57:102591.
2020
Davis JC, Alves TC, Helman A, Chen JC, Kenty JH, Cardone RL, Liu DR, Kibbey RG, Melton DA. Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis. Cell Rep. 2020;31(6):107623.
Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020;32(2):107894.
Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA. A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion. Cell Metab. 2020.
Rasouli N, Melton DA, Alvarez-Dominguez JR. Purification of Live Stem-Cell-Derived Islet Lineage Intermediates. Curr Protoc Stem Cell Biol. 2020;53(1):e111.
2019
Davis JC, Helman A, Rivera-Feliciano J, Langston CM, Engquist EN, Melton DA. Live Cell Monitoring and Enrichment of Stem Cell-Derived β Cells Using Intracellular Zinc Content as a Population Marker. Curr Protoc Stem Cell Biol. 2019;51(1):e99.
Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA. Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. Cell Rep. 2019;27(8):2281-2291.e5.
2016
Cox AR, Barrandon O, Cai EP, Rios JS, Chavez J, Bonnyman CW, Lam CJ, Yi P, Melton DA, Kushner JA. Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. PLoS One. 2016;11(7):e0159276.
2015
Kenty JHR, Melton DA. Testing Pancreatic Islet Function at the Single Cell Level by Calcium Influx with Associated Marker Expression. PLoS One. 2015;10(4):e0122044.
2014
Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FWalton, Diiorio P, Rezania A, Gifford DK, Melton DA. Differentiated human stem cells resemble fetal, not adult, β cells. Proc Natl Acad Sci U S A. 2014.
Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JHyoje, Peterson QP, Greiner D, Melton DA. Generation of Functional Human Pancreatic β Cells In Vitro. Cell. 2014;159(2):428-439.
Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA. Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway. Elife. 2014;3.
2013
Yi P, Park J-S, Melton DA. Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation. Cell. 2013.