Biblio
Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells. APL Bioeng. 2023;7(3):036107.
. Identifying biomarkers of heterogeneity and transplantation efficacy in retinal pigment epithelial cells. J Exp Med. 2023;220(12).
Improved Protocol for Reproducible Human Cortical Organoids Reveals Early Alterations in Metabolism with Mutations. bioRxiv. 2023.
Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report. Stem Cell Res Ther. 2023;14(1):53.
4D imaging analysis of the aging mouse neural stem cell niche reveals a dramatic loss of progenitor cell dynamism regulated by the RHO-ROCK pathway. Stem Cell Reports. 2022.
. Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Transl Psychiatry. 2022;12(1):508.
. Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol. Stem Cell Reports. 2022.
3D image analysis of the complete ventricular-subventricular zone stem cell niche reveals significant vasculature changes and progenitor deficits in males versus females with aging. Stem Cell Reports. 2021.
. Assessing patient perception of risk in ocular stem cell therapies. Stem Cell Reports. 2021.
ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021.
Mentorship in Science: Response to AlShebli et al., Nature Communications 2020. Stem Cell Reports. 2021;16(1):1-2.
. Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline. J Exp Med. 2020;217(4).
Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material. Invest Ophthalmol Vis Sci. 2019;60(10):3468-3479.
Regenerating Eye Tissues to Preserve and Restore Vision. Cell Stem Cell. 2018;23(3):453.
. Automated Measurement of Cobblestone Morphology for Characterizing Stem Cell Derived Retinal Pigment Epithelial Cell Cultures. J Ocul Pharmacol Ther. 2016.
. LEVER: software tools for segmentation, tracking and lineaging of proliferating cells. Bioinformatics. 2016.
. Computational Image Analysis Reveals Intrinsic Multigenerational Differences between Anterior and Posterior Cerebral Cortex Neural Progenitor Cells. Stem Cell Reports. 2015.
. Human Adult Retinal Pigment Epithelial Stem Cell-Derived RPE Monolayers Exhibit Key Physiological Characteristics of Native Tissue. Invest Ophthalmol Vis Sci. 2015;56(12):7085-7099.
It Takes a Village: Constructing the Neurogenic Niche. Dev Cell. 2015;32(4):435-446.
. Human RPE Stem Cells Grown into Polarized RPE Monolayers on a Polyester Matrix Are Maintained after Grafting into Rabbit Subretinal Space. Stem Cell Reports. 2014;2(1):64-77.
Interaction of Amyloid Inhibitor Proteins with Amyloid Beta Peptides: Insight from Molecular Dynamics Simulations. PLoS One. 2014;9(11):e113041.
. Multisensory interface for 5D stem cell image volumes. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1178-1181.
. Visualization and Correction of Automated Segmentation, Tracking and Lineaging from 5-D Stem Cell Image Sequences. BMC Bioinformatics. 2014;15(1):328.
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