Biblio

Author Title Type [ Year(Asc)]
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2024
Lim S, van Son GJF, Yanti NLuh Wisma, Andersson-Rolf A, Willemsen S, Korving J, Lee H-G, Begthel H, Clevers H. Derivation of functional thymic epithelial organoid lines from adult murine thymus. Cell Rep. 2024;43(4):114019.
Bannier-Hélaouët M, Korving J, Ma Z, Begthel H, Giladi A, Lamers MM, van de Wetering WJ, Yawata N, Yawata M, Lapointe VLS, et al. Human conjunctiva organoids to study ocular surface homeostasis and disease. Cell Stem Cell. 2024.
Hendriks D, Pagliaro A, Andreatta F, Ma Z, van Giessen J, Massalini S, Lopez-Iglesias C, van Son GJF, DeMartino J, J Damen MA, et al. Human fetal brain self-organizes into long-term expanding organoids. Cell. 2024.
2023
Li Y, Chaurasia B, M Rahman M, Kaddai V, J Maschek A, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, et al. Ceramides increase fatty acid utilization in intestinal progenitors to enhance stemness and increase tumor risk. Gastroenterology. 2023.
Yang ASP, Dutta D, Kretzschmar K, Hendriks D, Puschhof J, Hu H, Boonekamp KE, van Waardenburg Y, Lopes SMChuva de, van Gemert G-J, et al. Development of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid cultures. Nat Commun. 2023;14(1):4631.
San Juan L, Freije A, Sanz-Gómez N, Jiménez-Matías B, Pleguezuelos-Manzano C, J Sanz R, de Diego E, Naranjo S, Clevers H, Gandarillas A. DNA damage triggers squamous metaplasia in human lung and mammary cells via mitotic checkpoints. Cell Death Discov. 2023;9(1):21.
Visser LL, Bleijs M, Margaritis T, van de Wetering M, Holstege FC, Clevers H. Ewing sarcoma single-cell transcriptome analysis reveals functionally impaired antigen-presenting cells. Cancer Res Commun. 2023.
Xu X, Kumari R, Zhou J, Chen J, Mao B, Wang J, Zheng M, Tu X, An X, Chen X, et al. A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology. PLoS One. 2023;18(1):e0279821.
Sell T, Klotz C, Fischer MM, Astaburuaga-García R, Krug S, Drost J, Clevers H, Sers C, Morkel M, Blüthgen N. Oncogenic signaling is coupled to colorectal cancer cell differentiation state. J Cell Biol. 2023;222(6).
Zheng X, Betjes MA, Ender P, Goos YJ, Huelsz-Prince G, Clevers H, van Zon JS, Tans SJ. Organoid cell fate dynamics in space and time. Sci Adv. 2023;9(33):eadd6480.
Sporrij A, Choudhuri A, Prasad M, Muhire B, Fast EM, Manning ME, Weiss JD, Koh M, Yang S, Kingston RE, et al. PGE alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate. Proc Natl Acad Sci U S A. 2023;120(19):e2220613120.
Jordan R, Ford-Scheimer SL, Alarcon RM, Atala A, Borenstein JT, Brimacombe KR, Cherry S, Clevers H, Davis MI, Funnell SGP, et al. Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. J Infect Dis. 2023.
Pradeu T, Daignan-Fornier B, Ewald A, Germain P-L, Okasha S, Plutynski A, Benzekry S, Bertolaso M, Bissell M, Brown JS, et al. Reuniting philosophy and science to advance cancer research. Biol Rev Camb Philos Soc. 2023.
Pagliaro A, Finger R, Zoutendijk I, Bunschuh S, Clevers H, Hendriks D, Artegiani B. Temporal morphogen gradient-driven neural induction shapes single expanded neuroepithelium brain organoids with enhanced cortical identity. Nat Commun. 2023;14(1):7361.
Yengej FAYousef, Jansen J, Ammerlaan CME, Dilmen E, Casellas CPou, Masereeuw R, Hoenderop JG, Smeets B, Rookmaaker MB, Verhaar MC, et al. Tubuloid culture enables long-term expansion of functional human kidney tubule epithelium from iPSC-derived organoids. Proc Natl Acad Sci U S A. 2023;120(6):e2216836120.
2022
Beumer J, Puschhof J, Yengej FYousef, Zhao L, Martinez-Silgado A, Blotenburg M, Begthel H, Boot C, van Oudenaarden A, Chen Y-G, et al. BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states. Cell Rep. 2022;38(9):110438.
Narayan NJC, Requena D, Lalazar G, Ramos-Espiritu L, Ng D, Levin S, Shebl B, Wang R, Hammond WJ, Saltsman JA, et al. Human liver organoids for disease modeling of fibrolamellar carcinoma. Stem Cell Reports. 2022.
Stenudd M, Sabelström H, Llorens-Bobadilla E, Zamboni M, Blom H, Brismar H, Zhang S, Basak O, Clevers H, Göritz C, et al. Identification of a discrete subpopulation of spinal cord ependymal cells with neural stem cell properties. Cell Rep. 2022;38(9):110440.
Lucas C, Sauter K-S, Steigert M, Mallet D, Wilmouth J, Olabe J, Plotton I, Morel Y, Aeberli D, Wagner F, et al. Loss of LGR4/GPR48 causes severe neonatal salt-wasting due to disrupted WNT signaling altering adrenal zonation. J Clin Invest. 2022.
He G-W, Lin L, DeMartino J, Zheng X, Staliarova N, Dayton T, Begthel H, van de Wetering WJ, Bodewes E, van Zon J, et al. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 2022.
Wang Z, Boretto M, Millen R, Natesh N, Reckzeh ES, Hsu C, Negrete M, Yao H, Quayle W, Heaton BE, et al. Rapid tissue prototyping with micro-organospheres. Stem Cell Reports. 2022.
2021
Bannier-Hélaouët M, Post Y, Korving J, Bustos MTrani, Gehart H, Begthel H, Bar-Ephraim YE, van der Vaart J, Kalmann R, Imhoff SM, et al. Exploring the human lacrimal gland using organoids and single-cell sequencing. Cell Stem Cell. 2021.
Busslinger GA, Weusten BLA, Bogte A, Begthel H, Brosens LAA, Clevers H. Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution. Cell Rep. 2021;34(10):108819.
Boonekamp KElisabeth, Heo I, Artegiani B, Asra P, van Son G, de Ligt J, Clevers H. Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids. Dev Biol. 2021.
Hynds RE, Zacharias WJ, Nikolić MZ, Königshoff M, Eickelberg O, Gosens R, De Coppi P, Janes SM, Morrisey E, Clevers H, et al. National Heart, Lung and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration. Am J Respir Cell Mol Biol. 2021.

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