Jay Bradner on open source drug discovery, cancer, and targeting the epigenome
James “Jay “ Bradner, M.D. is an Assistant Professor of Medicine at Harvard Medical School, Investigator and Staff Physician at the Dana-Farber Cancer Institute, Associate Member of the Chemical Biology Program at the Broad Institute and Affiliate Faculty member of the Harvard Stem Cell Institute. His lab is focused on chemical biological approaches to studying chromatin- associated complexes with a focus on oncology. His achievements in promoting open source drug discovery have the potential to change how cancer and disease therapies are developed. Jay spoke with the StemBook editor, Lisa Girard, about his work creating chemical tools to fight cancer, his innovative approach to distributing these tools as a means of accelerating discovery, and how this just might change how pharma thinks about making medicines.